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Genomic diversity of individual lung tumors revealed(Science, Oct 10, 2014)
2014-10-14 10:42 written by ercsb (2025-02-05 17:54 Modify)
Untitled document

 

Date : October 9, 2014
Source : University of Texas M. D. Anderson Cancer Center

Summary:
The challenge of what scientists call genomic heterogeneity, the presence of many different variations that drive tumor formation, growth and progression, has now been addressed by scientists. The researchers conducted whole exome sequencing on 48 tumor regions from 11 surgically removed localized lung adenocarcinomas, cancers that form in the epithelial tissue that lines the lung. Surgery for these non-small cell lung cancers is potentially curative.

 

 

 

Story Source:

The above story is based on materials provided by University of Texas M. D. Anderson Cancer Center. Note: Materials may be edited for content and length.

 

Journal Reference:

  1. J. Zhang, J. Fujimoto, J. Zhang, D. C. Wedge, X. Song, J. Zhang, S. Seth, C.-W. Chow, Y. Cao, C. Gumbs, K. A. Gold, N. Kalhor, L. Little, H. Mahadeshwar, C. Moran, A. Protopopov, H. Sun, J. Tang, X. Wu, Y. Ye, W. N. William, J. J. Lee, J. V. Heymach, W. K. Hong, S. Swisher, I. I. Wistuba, P. A. Futreal. Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing. Science, 2014; 346 (6206): 256 DOI: 10.1126/science.1256930

Cite This Page:

University of Texas M. D. Anderson Cancer Center. "Genomic diversity of individual lung tumors revealed." ScienceDaily. ScienceDaily, 9 October 2014. <www.sciencedaily.com/releases/2014/10/141009153813.htm>.
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